Source of Chronic Inflammation in Aging

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Source of Chronic Inflammation in Aging

Aging is a complex process that results from a combination of environmental, genetic, and epigenetic factors. A chronic pro-inflammatory status is a pervasive feature of aging. This chronic low-grade inflammation occurring in the absence of overt infection has been defined as "inflammaging" and represents a significant risk factor for morbidity and mortality in the elderly. The low-grade inflam...

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Chronic inflammation as a determinant of future aging phenotypes.

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Aging and Inflammation

Chronic systemic inflammation is an underlying cause of many seemingly unrelated, age-related diseases. As humans grow older, systemic inflammation can inflict devastating degenerative effects throughout the body (Ward 1995; McCarty 1999; Brod 2000). This fact is often overlooked by the medical establishment, yet persuasive scientific evidence exists that correcting a chronic inflammatory disor...

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ژورنال

عنوان ژورنال: Frontiers in Cardiovascular Medicine

سال: 2018

ISSN: 2297-055X

DOI: 10.3389/fcvm.2018.00012